| Title | Psychological Distress Is Prevalent and Interdependent Among Patients With Decompensated Cirrhosis and Their Caregivers. |
| Publication Type | Journal Article |
| Year of Publication | 2025 |
| Authors | Ufere NN, Zeng C, Donlan J, Shalev D, Kaplan A, Noll A, Liu A, Pintro K, Horick N, Indriolo T, Li L, Zhu E, Armstrong ME, Mason N, Engel KG, Rowland M, O'Brien K, Kenimer S, Diop MS, Jackson V, Lai JC, Chung RT, Jacobs JM, Edelen MO, El-Jawahri A |
| Journal | Am J Gastroenterol |
| Volume | 120 |
| Issue | 4 |
| Pagination | 909-913 |
| Date Published | 2025 Apr 01 |
| ISSN | 1572-0241 |
| Keywords | Adult, Aged, Anxiety, Caregivers, Cross-Sectional Studies, Depression, Female, Humans, Liver Cirrhosis, Male, Middle Aged, Prevalence, Psychological Distress, Stress, Psychological |
| Abstract | INTRODUCTION: Little is known about the interdependence of psychological distress among patients with decompensated cirrhosis and their caregivers. METHODS: In this cross-sectional study, we examined the interdependence of psychological distress (Hospital Anxiety and Depression Scale) among 127 patient-caregiver dyads using Actor-Partner Interdependence Modeling. RESULTS: Among dyads, 26% had both partners reporting clinically significant anxiety and 18% reporting clinically significant depression. Caregiver anxiety significantly predicted patient depression (standardized β = 0.18, P = 0.03). DISCUSSION: Psychological distress was prevalent and interdependent among dyads. These results underscore the need to develop interventions to reduce psychological distress in both patients with decompensated cirrhosis and their caregivers. |
| DOI | 10.14309/ajg.0000000000003158 |
| Alternate Journal | Am J Gastroenterol |
| PubMed ID | 39450861 |
| Grant List | Clinical, Translational and Outcomes Research Award / / American Association for the Study of Liver Diseases / Sojourns Scholar Leadership Program Award / / Cambia Health Foundation / |